Searchable abstracts of presentations at key conferences in endocrinology

ea0031s6.1 | Making the glucocorticoid clock run smoothly (Supported by Addison's Disease self-help group) | SFEBES2013

Monitoring glucocorticoid signaling and circadian clock function with transgenic zebrafish reporter lines

Weger Benjamin D , Weger Meltem , Diotel Nicolas , Nusser Michael , Rastegar Sepand , Hirota Tsuyoshi , Kay Steve A. , Strahle Uwe , Brenner-Weiss Gerald , Dickmeis Thomas

Due to its rapid development and high fecundity, the zebrafish is a standard model in developmental biology and genetics. Furthermore, key hormone systems present in mammals are already active in zebrafish larvae. The endocrine system and the circadian clock are closely linked, and also the circadian system of zebrafish matures early in development. The small size of zebrafish larvae makes them particularly suitable for chemical screens in vivo: Larvae can be kept for...